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Elubrixin

Product Specifications

CAS Number

688763-64-6

Target

IL Receptor, CXCR, Interleukin

Related Pathways

GPCR/G Protein, Autophagy, Immunology/Inflammation

Purity

>99.99%

Bioactivity

Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM) . Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.

Smiles

S(=O)(=O)(C1=C(O)C(NC(NC2=C(Cl)C(F)=CC=C2)=O)=CC=C1Cl)N3CCNCC3

Molecular Formula

C17H17Cl2FN4O4S

Molecular Weight

463.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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