Elubrixin
Product Specifications
CAS Number
688763-64-6
Target
IL Receptor|||CXCR|||Interleukin
Related Pathways
GPCR/G Protein|||Autophagy|||Immunology/Inflammation
Purity
>99.99%
Bioactivity
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM) . Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
Smiles
S(=O)(=O)(C1=C(O)C(NC(NC2=C(Cl)C(F)=CC=C2)=O)=CC=C1Cl)N3CCNCC3
Molecular Formula
C17H17Cl2FN4O4S
Molecular Weight
463.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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