ELN318463
Product Specifications
CAS Number
851600-86-7
Target
Others, Gamma-secretase
Related Pathways
Stem Cells, Proteases/Proteasome, Others, Neuroscience
Bioactivity
ELN 318463 shows differential inhibition of presenilin (PS1) - and PS2-comprised γ-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
Smiles
Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)cc1)[C@@H]1CCCCNC1=O
Molecular Formula
C19H20BrClN2O3S
Molecular Weight
471.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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