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ELN318463

Product Specifications

CAS Number

851600-86-7

Target

Others|||Gamma-secretase

Related Pathways

Stem Cells|||Proteases/Proteasome|||Others|||Neuroscience

Bioactivity

ELN 318463 shows differential inhibition of presenilin (PS1) - and PS2-comprised ?-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyloid precursor protein (APP) selective ?-secretase inhibitor.

Smiles

Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)cc1)[C@@H]1CCCCNC1=O

Molecular Formula

C19H20BrClN2O3S

Molecular Weight

471.8

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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