EIF4A3-IN-1
Product Specifications
CAS Number
2095486-67-0
Target
PERK
Related Pathways
Apoptosis
Purity
0.9989
Bioactivity
EIF4A3-IN-1 is a selective and potent inhibitor of eukaryotic initiation factor 4A3 (eIF4A3) with an IC50 value of 0.26 μM. eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.
Smiles
C(=O)(N1[C@H](CN(C(=O)C2=C(C)N(N=C2)C3=CC(C#N)=CC=C3)CC1)C4=CC=C(Cl)C=C4)C5=CC=C(Br)C=C5
Molecular Formula
C29H23BrClN5O2
Molecular Weight
588.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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