Quabodepistat
Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1].
Product Specifications
CAS Number
1883747-71-4
Product Name Alternative
OPC-167832
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/quabodepistat.html
Purity
98.00
Solubility
DMSO : 180 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C(OC[C@@]3(O)[C@H](O)CN(C4=C(F)C=C(Cl)C=C4F)CC3)=CC=C2F)CC1
Molecular Formula
C21H20ClF3N2O4
Molecular Weight
456.84
References & Citations
[1]Norimitsu Hariguchi, et al. OPC-167832, a Novel Carbostyril Derivative with Potent Antituberculosis Activity as a DprE1 Inhibitor.Antimicrob Agents Chemother. 2020 May 21;64 (6) :e02020-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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