EGFR-IN-5

Product Specifications

CAS Number

2225887-26-1

Target

EGFR

Related Pathways

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

Purity

0.9817

Bioactivity

EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR (L858R), EGFR (L858R/T790M), and EGFR (L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.

Smiles

N(C=1N=C(C2=C(N1)C=NC(NC3=CC=C(C=N3)N4CCC(N(C)C)CC4)=C2)N5CCC(CO)CC5)C6=CC=C(F)C=C6

Molecular Formula

C31H38FN9O

Molecular Weight

571.69

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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