EGFR-IN-5
Product Specifications
CAS Number
2225887-26-1
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Purity
0.9817
Bioactivity
EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR (L858R), EGFR (L858R/T790M), and EGFR (L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.
Smiles
N(C=1N=C(C2=C(N1)C=NC(NC3=CC=C(C=N3)N4CCC(N(C)C)CC4)=C2)N5CCC(CO)CC5)C6=CC=C(F)C=C6
Molecular Formula
C31H38FN9O
Molecular Weight
571.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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