Nazartinib mesylate
Product Specifications
CAS Number
1508250-72-3
Target
Others, EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Others, JAK/STAT signaling
Bioactivity
Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR (L858R/790M) mutant) .
Smiles
S(C)(=O)(=O)O.N(C(=O)C=1C=C(C)N=CC1)C=2N(C=3C(N2)=CC=CC3Cl)[C@]4(CN(C(/C=C/CN(C)C)=O)CCCC4)[H]
Molecular Formula
C27H35ClN6O5S
Molecular Weight
591.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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