EG01377
Product Specifications
CAS Number
2227996-00-9
Target
Others, Complement System
Related Pathways
Others, Immunology/Inflammation
Bioactivity
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.
Smiles
S(NC1=C(C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)SC=C1)(=O)(=O)C2=C3C(=CC(=C2)C4=CC=C(CN)C=C4)CCO3
Molecular Formula
C26H30N6O6S2
Molecular Weight
586.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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