EG00229
Product Specifications
CAS Number
1210945-69-9
Target
Complement System, Others
Related Pathways
Immunology/Inflammation, Others
Purity
0.9823
Bioactivity
EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain with an IC50 value of 3 μM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2.
Smiles
OC(=O)C(F)(F)F.NC(=N)NCCC[C@H](NC(=O)c1sccc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O
Molecular Formula
C19H20F3N7O7S3
Molecular Weight
611.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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