EB-47
Product Specifications
CAS Number
366454-36-6
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9986
Bioactivity
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.
Smiles
O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C(=O)N4CCN(CC(NC5=C6C(C(=O)NC6)=CC=C5)=O)CC4)[C@H]1O
Molecular Formula
C24H27N9O6
Molecular Weight
537.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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