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(E/Z) -BCI

Product Specifications

CAS Number

15982-84-0

Target

Phosphatase|||Apoptosis

Related Pathways

Apoptosis|||Metabolism

Purity

0.9994

Bioactivity

(E/Z) -BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-?B pathway.

Smiles

O=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12

Molecular Formula

C22H23NO

Molecular Weight

317.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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