DZ2002
Product Specifications
CAS Number
33231-14-0
Target
Antibacterial|||Antibiotic|||Akt|||NF-?B|||MEK|||ERK|||STAT|||Others|||PI3K
Related Pathways
JAK/STAT signaling|||Cytoskeletal Signaling|||MAPK|||NF-?B|||PI3K/Akt/mTOR signaling|||Others|||Microbiology/Virology|||Stem Cells
Purity
0.9991
Bioactivity
DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity. It effectively prevents experimental dermal fibrosis by reversing the profibrotic phenotype in multiple cell types, making it useful for studying autoimmune diseases like lupus syndrome and systemic sclerosis.
Smiles
COC(=O)C(O)CCn1cnc2c(N)ncnc12
Molecular Formula
C10H13N5O3
Molecular Weight
251.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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