Duocarmycin DM free base
Product Specifications
CAS Number
1116745-06-2
Target
DNA Alkylator/Crosslinker, ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.
Smiles
CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21
Molecular Formula
C26H26ClN3O3
Molecular Weight
463.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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