DRI-C21045
Product Specifications
CAS Number
2101765-81-3
Target
NF-κB, TNF
Related Pathways
NF-κB, Apoptosis
Purity
0.981
Bioactivity
Dri-c21045 showed concentration-dependent inhibition of NF-kB activation and all CD40L induced by B cell proliferation with IC50 of 17.1 μM and 4.5 μM, respectively. Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein interaction (PPI) with IC50 of 0.17 μM.
Smiles
COC(=O)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc2cccc(c12)S(O)(=O)=O
Molecular Formula
C32H24N2O7S
Molecular Weight
580.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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