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Dot1L-IN-5

Product Specifications

CAS Number

2565705-03-3

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein (DOT1L) with an IC 50 SPA DOT1L of 0.17 nM [1].

Smiles

COc1nc(N)nc(Nc2cc(ccc2N[C@@H](c2cccc3OC(F)(F)Oc23)c2ncccc2Cl)S(N)(=O)=O)n1

Molecular Formula

C23H19ClF2N8O5S

Molecular Weight

592.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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