Dot1L-IN-2
Product Specifications
CAS Number
1940206-71-2
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectively.
Smiles
CC=1N(C=2C(C1)=CC=C(NC=3N=C(NC)C=CN3)C2)C4=C(OC=5C=C6C(=NC5)N(C)C=N6)C=CC=C4
Molecular Formula
C27H24N8O
Molecular Weight
476.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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