Dot1L-IN-2

Product Specifications

CAS Number

1940206-71-2

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectively.

Smiles

CC=1N(C=2C(C1)=CC=C(NC=3N=C(NC)C=CN3)C2)C4=C(OC=5C=C6C(=NC5)N(C)C=N6)C=CC=C4

Molecular Formula

C27H24N8O

Molecular Weight

476.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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