DM3
Product Specifications
CAS Number
796073-54-6
Target
Microtubule Associated, ADC Cytotoxin
Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Bioactivity
DM3 (Maytansinoid DM3) is a maytansine mimic with disulfide or thiol groups, acting as a tubulin inhibitor and serving as the cytotoxic component in antibody-drug conjugates (ADCs) .
Smiles
[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@]([H])(OC(=O)[C@H](C)N(C)C(=O)CCC(C)S)[C@]1(C)O[C@H]1[C@@H]2C
Molecular Formula
C37H52ClN3O10S
Molecular Weight
766.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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