Dihydrocytochalasin B
Product Specifications
CAS Number
39156-67-7
Target
Arp2/3 Complex, Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that prevents cytokinesis, alters cell morphology, disrupts actin structures in Swiss/3T3 mouse fibroblasts, and inhibits DNA synthesis induced by serum growth factors in quiescent cultures. Low doses of H2CB lead to cell rounding and the loss of actin microfilament bundles.
Smiles
O=C1[C@]23[C@]([C@H](CC4=CC=CC=C4)N1)([C@H](C)C(=C)[C@@H](O)[C@@]2(/C=C/C[C@H](C)CCC[C@@H](O)CCC(=O)O3)[H])[H]
Molecular Formula
C29H39NO5
Molecular Weight
481.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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