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DHODH-IN-3

Product Specifications

CAS Number

1148126-04-8

Target

Others, Dehydrogenase, DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint, Metabolism

Bioactivity

DHODH-IN-3 is an effective inhibitor of human dihydroorotate dehydrogenase (HsDHODH) with IC50 value of 261 nM. DHODH-IN-3 binds to the ubiquinone binding cavity in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential to treat malaria.

Smiles

ClC=1C=C(C=CC1NC(/C(=C(/C)\O)/C#N)=O)C2=CC=CC=C2

Molecular Formula

C17H13ClN2O2

Molecular Weight

312.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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