DHODH-IN-3
Product Specifications
CAS Number
1148126-04-8
Target
Others, Dehydrogenase, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint, Metabolism
Bioactivity
DHODH-IN-3 is an effective inhibitor of human dihydroorotate dehydrogenase (HsDHODH) with IC50 value of 261 nM. DHODH-IN-3 binds to the ubiquinone binding cavity in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential to treat malaria.
Smiles
ClC=1C=C(C=CC1NC(/C(=C(/C)\O)/C#N)=O)C2=CC=CC=C2
Molecular Formula
C17H13ClN2O2
Molecular Weight
312.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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