DC41SMe
Product Specifications
CAS Number
1354787-71-5
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used for targeted treatment of cancer.
Smiles
C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC(NC(=O)C=5NC=6C(C5)=CC(NC(CCC(SSC)(C)C)=O)=CC6)=CC4)C1)C=C(O)C=7C2=CC=CC7
Molecular Formula
C38H36ClN5O4S2
Molecular Weight
726.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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