DC10SMe
Product Specifications
Target
DNA Alkylator/Crosslinker, ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
DC10SMe is a DNA alkylating agent that can be used in the synthesis of antibody-drug conjugates (ADC) . The IC50 of DC10SMe for Ramos, Namalwa and HL60 / s cancer cells were 15 pM, 12 pM and 12 pM, respectively.
Smiles
O=C(C1=CC2=C(C=CC(NC(CCSSC)=O)=C2)N1)NC3=CC4=C(C=C3)NC(C(N5C(C67[C@H](C7)C5)=CC(C8=C6C=CC=C8)=O)=O)=C4
Molecular Formula
C35H29N5O4S2
Molecular Weight
647.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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