DC1SMe
Product Specifications
CAS Number
501666-85-9
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60 / s and COLO 205 cancer cells of 22pm, 10pm, 32pm and 250pm, respectively.
Smiles
C(Cl)[C@H]1C2=C(N(C(=O)C3=CC=4C(N3)=CC=C(NC(=O)C5=CC=6C(N5)=CC=C(NC(CCSSC)=O)C6)C4)C1)C=C(O)C=7C2=CC=CC7
Molecular Formula
C35H30ClN5O4S2
Molecular Weight
684.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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