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Darbufelone

Product Specifications

CAS Number

139226-28-1

Target

Prostaglandin Receptor, LTR, Leukotriene Receptor

Related Pathways

Immunology/Inflammation, GPCR/G Protein

Purity

0.9977

Bioactivity

Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF2α and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGHS-2 and PGHS-1.

Smiles

C(\C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=C\2/C(=O)N=C(N)S2

Molecular Formula

C18H24N2O2S

Molecular Weight

332.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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