Darbufelone
Product Specifications
CAS Number
139226-28-1
Target
Prostaglandin Receptor, LTR, Leukotriene Receptor
Related Pathways
Immunology/Inflammation, GPCR/G Protein
Purity
0.9977
Bioactivity
Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF2α and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGHS-2 and PGHS-1.
Smiles
C(\C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=C\2/C(=O)N=C(N)S2
Molecular Formula
C18H24N2O2S
Molecular Weight
332.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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