Darbufelone

Product Specifications

CAS Number

139226-28-1

Target

Prostaglandin Receptor|||LTR|||Leukotriene Receptor

Related Pathways

Immunology/Inflammation|||GPCR/G Protein

Purity

0.9977

Bioactivity

Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF2? and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 ?M and IC50s of 0.19 ?M and 20 ?M for PGHS-2 and PGHS-1.

Smiles

C(\C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=C\2/C(=O)N=C(N)S2

Molecular Formula

C18H24N2O2S

Molecular Weight

332.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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