Cytochalasin A
Product Specifications
CAS Number
14110-64-6
Target
Antifungal, HIV Protease
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Bioactivity
Cytochalasin A, a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, is an inhibitor of HIV-1 protease (IC50 = 3 μM) . It inhibits actin polymerization, interferes with microtubule assembly by reacting with sulfhydryl groups, and serves as an antibiotic and bactericidal active agent.
Smiles
[H][C@]12[C@H](Cc3ccccc3)NC(=O)C11OC(=O)\C=C\C(=O)CCC[C@@H](C)C\C=C\C1[C@H](O)C(=C)[C@H]2C
Molecular Formula
C29H35NO5
Molecular Weight
477.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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