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Cytochalasin A

Product Specifications

CAS Number

14110-64-6

Target

Antifungal, HIV Protease

Related Pathways

Proteases/Proteasome, Microbiology/Virology

Bioactivity

Cytochalasin A, a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, is an inhibitor of HIV-1 protease (IC50 = 3 μM) . It inhibits actin polymerization, interferes with microtubule assembly by reacting with sulfhydryl groups, and serves as an antibiotic and bactericidal active agent.

Smiles

[H][C@]12[C@H](Cc3ccccc3)NC(=O)C11OC(=O)\C=C\C(=O)CCC[C@@H](C)C\C=C\C1[C@H](O)C(=C)[C@H]2C

Molecular Formula

C29H35NO5

Molecular Weight

477.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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