CSN5i-3
Product Specifications
CAS Number
2375740-98-8
Target
Apoptosis, Others
Related Pathways
Others, Apoptosis
Purity
>99.99%
Bioactivity
CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5. It inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM. CSN5i-3 has a killing effect on a variety of cancer cells and can be used as an anticancer drug. [2]
Smiles
CC(C)n1nc(cc1C(=O)Nc1ccc([C@H]2[C@@H](O)CCCc3cncn23)c(c1)-c1ccccc1)C(F)F
Molecular Formula
C28H29F2N5O2
Molecular Weight
505.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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