CRT0066854 hydrochloride
Product Specifications
CAS Number
2250019-91-9
Target
ROCK, PKC
Related Pathways
Cell Cycle/Checkpoint, Chromatin/Epigenetic, Stem Cells, Cytoskeletal Signaling
Purity
0.9963
Bioactivity
CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
Smiles
N[C@@H](CC1=CC=CC=C1)CNC2=C3C4=C(CCCC4)SC3=NC(C5=CC=NC=C5)=N2.Cl.Cl
Molecular Formula
C24H27Cl2N5S
Molecular Weight
488.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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