CRA-026440
Product Specifications
CAS Number
847460-34-8
Target
Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis
Purity
0.9642
Bioactivity
CRA-026440 (PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-angiogenic activity and can be used to study colon cancer.
Smiles
O=C(NO)C1=CC=C(C#CCNC(=O)C2=CC=3C=C(OCCN(C)C)C=CC3N2)C=C1
Molecular Formula
C23H24N4O4
Molecular Weight
420.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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