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CP-547632

Product Specifications

CAS Number

252003-65-9

Target

PDGFR|||BTK|||FGFR|||VEGFR

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis

Purity

0.9939

Bioactivity

CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFR? and related tyrosine kinases (TKs) . PDGFR? and related tyrosine kinases (TKs) CP-547632 has antitumour activity.

Smiles

NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F

Molecular Formula

C20H24BrF2N5O3S

Molecular Weight

532.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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