CP-547632
Product Specifications
CAS Number
252003-65-9
Target
PDGFR|||BTK|||FGFR|||VEGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.9939
Bioactivity
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFR? and related tyrosine kinases (TKs) . PDGFR? and related tyrosine kinases (TKs) CP-547632 has antitumour activity.
Smiles
NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F
Molecular Formula
C20H24BrF2N5O3S
Molecular Weight
532.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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