CKI-7 free base
Product Specifications
CAS Number
120615-25-0
Target
Casein Kinase, SGK, S6 Kinase, CDK
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells, Metabolism, Cell Cycle/Checkpoint, MAPK
Bioactivity
CKI-7 free base is a potent, ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor, also inhibiting SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
Smiles
NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
Molecular Formula
C11H12ClN3O2S
Molecular Weight
285.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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