Chromomycin A3
Product Specifications
CAS Number
7059-24-7
Target
Antifungal, DNA/RNA Synthesis, Apoptosis, DNA Alkylation, DNA Alkylator/Crosslinker, Caspase, Antibacterial, Antibiotic
Related Pathways
Proteases/Proteasome, Cell Cycle/Checkpoint, Apoptosis, Microbiology/Virology, DNA Damage/DNA Repair
Bioactivity
Chromomycin A3 is an antibiotic produced by Streptomyces sp that binds to gc-rich DNA sequences in the presence of divalent cations and inhibits DNA replication and transcription; it is also used as a fluorescent DNA stain and assay; and it has anticancer activity against diseases such as Hodgkin's, lung adenocarcinomas, melanomas, and breast cancer.
Smiles
O=C1C=2C(C[C@@]([C@@H](C([C@H]([C@@H](C)O)O)=O)OC)([C@@H]1O[C@H]3C[C@@H](O[C@H]4C[C@@H](O[C@H]5C[C@](C)(O)[C@@H](OC(C)=O)[C@H](C)O5)[C@H](O)[C@@H](C)O4)[C@H](O)[C@@H](C)O3)[H])=CC=6C(C2O)=C(O)C(C)=C(O[C@H]7C[C@@H](O[C@@H]8C[C@@H](O)[C@@H](OC)[C@@H](C)O8)[C@@H](OC(C)=O)[C@@H](C)O7)C6
Molecular Formula
C57H82O26
Molecular Weight
1183.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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