CHPG
Product Specifications
CAS Number
170846-74-9
Target
Akt, Dehydrogenase, NF-κB, ERK, GluR
Related Pathways
Neuroscience, Cytoskeletal Signaling, MAPK, PI3K/Akt/mTOR signaling, NF-κB, Metabolism
Bioactivity
CHPG is a selective mGluR5 agonist that reduces LDH release and neuronal apoptosis, activates the ERK and Akt pathways, and protects against traumatic brain injury. It also increases the number of differentiated human OPCs and alleviates LPS-induced inflammation.
Smiles
O=C(O)C(N)C1=CC(O)=CC=C1Cl
Molecular Formula
C8H8ClNO3
Molecular Weight
201.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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