CHMFL-EGFR-202
Product Specifications
CAS Number
2089381-40-6
Target
BTK, MEK, EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, MAPK, Tyrosine Kinase/Adaptors
Purity
0.9966
Bioactivity
CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase with IC50 values of 5.3 nM for drug-resistant mutant EGFR T790M and 8.3 nM for WT EGFR kinases.
Smiles
NC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4
Molecular Formula
C25H24ClN7O2
Molecular Weight
489.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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