CHMFL-EGFR-202
Product Specifications
CAS Number
2089381-40-6
Target
BTK, MEK, EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, MAPK, Tyrosine Kinase/Adaptors
Purity
0.9966
Bioactivity
CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase with IC50 values of 5.3 nM for drug-resistant mutant EGFR T790M and 8.3 nM for WT EGFR kinases.
Smiles
NC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4
Molecular Formula
C25H24ClN7O2
Molecular Weight
489.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7060536-01 0.02 mg (E-Coli)
Recombinant Measles virus Hemagglutinin glycoprotein (H), partial
Sign In for Pricing
View Details MBS7060536-02 0.02 mg (Yeast)
Recombinant Measles virus Hemagglutinin glycoprotein (H), partial
Sign In for Pricing
View Details MBS7060536-03 0.1 mg (E-Coli)
Recombinant Measles virus Hemagglutinin glycoprotein (H), partial
Sign In for Pricing
View Details MBS7060536-04 0.1 mg (Yeast)
Recombinant Measles virus Hemagglutinin glycoprotein (H), partial
Sign In for Pricing
View Details