CGP52411
Product Specifications
CAS Number
145915-58-8
Target
Beta Amyloid|||EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Neuroscience|||Angiogenesis
Purity
0.9978
Bioactivity
CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 ?M) . CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of ?-amyloid A?42 fibril aggregates. CGP52411 can be used in studies about Alzheimer's diseases.
Smiles
O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12
Molecular Formula
C20H15N3O2
Molecular Weight
329.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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