Resiquimod-d5

Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2].

Product Specifications

CAS Number

[2252319-44-9]

Product Name Alternative

R848-d5; S28463-d5

UNSPSC

12352005

Target

HCV; Isotope-Labeled Compounds; Toll-like Receptor (TLR)

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Immunology/Inflammation; Others

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Purity

99.84

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 0.1mg/mL (ultrasonic)

Smiles

CC(C)(O)CN1C2=C(N=C1COC([2H])([2H])C([2H])([2H])[2H])C(N)=NC3=CC=CC=C23

Molecular Formula

C17H17D5N4O2

Molecular Weight

319.41

References & Citations

[1]Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33 (36) :4526-32.|[2]Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus) . Dev Comp Immunol. 2015 Mar;49 (1) :113-20.