CDK8/19-IN-1
Product Specifications
CAS Number
1818427-07-4
Target
ASK, CDK
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Bioactivity
CDK8/19-IN-1 is a selective, orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM for CDK8, 0.99 nM for CDK19, and 270 nM for [CDK9].
Smiles
O(C1=C2C(=C(C(N)=O)S1)CCC3=C2SN=C3)C=4C=CC(C(NCCOC)=O)=NC4
Molecular Formula
C19H18N4O4S2
Molecular Weight
430.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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