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CDK8/19-IN-1

Product Specifications

CAS Number

1818427-07-4

Target

ASK|||CDK

Related Pathways

Cell Cycle/Checkpoint|||Apoptosis

Bioactivity

CDK8/19-IN-1 is a selective, orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM for CDK8, 0.99 nM for CDK19, and 270 nM for [CDK9].

Smiles

O(C1=C2C(=C(C(N)=O)S1)CCC3=C2SN=C3)C=4C=CC(C(NCCOC)=O)=NC4

Molecular Formula

C19H18N4O4S2

Molecular Weight

430.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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