CDK4/6-IN-3
Product Specifications
CAS Number
2366237-37-6
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK4/6-IN-3, a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM), is used for the treatment of glioblastoma and inhibits CDK1 with a Ki of 110 nM.
Smiles
C(C)N1CC2(CN(C2)C=3C=CC(NC=4N=C(C(F)=CN4)C5=C6N(N=C5)CCCC[C@H]6C)=NC3)C1
Molecular Formula
C25H31FN8
Molecular Weight
462.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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