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CDK4/6-IN-3

Product Specifications

CAS Number

2366237-37-6

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Bioactivity

CDK4/6-IN-3, a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM), is used for the treatment of glioblastoma and inhibits CDK1 with a Ki of 110 nM.

Smiles

C(C)N1CC2(CN(C2)C=3C=CC(NC=4N=C(C(F)=CN4)C5=C6N(N=C5)CCCC[C@H]6C)=NC3)C1

Molecular Formula

C25H31FN8

Molecular Weight

462.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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