CCR7 Ligand 1
Product Specifications
CAS Number
681514-83-0
Target
CCR, Ligands for Target Protein for PROTAC, Others
Related Pathways
Immunology/Inflammation, Microbiology/Virology, GPCR/G Protein, PROTAC, Others
Bioactivity
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. This thiadiazole-dioxide ligand suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
Smiles
CN(C)C(=O)c1c(C)ccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O
Molecular Formula
C22H29N5O5S
Molecular Weight
475.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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