CCR1 antagonist 9
Product Specifications
CAS Number
1220026-26-5
Target
CCR
Related Pathways
Microbiology/Virology, GPCR/G Protein, Immunology/Inflammation
Purity
0.9913
Bioactivity
CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. It exhibits an IC50 of 6.8 nM for CCR1 inhibition in calcium flux assays and an IC50 of 30 μM for hERG.
Smiles
O=C(NCC=1C=CN=C(C1)S(=O)(=O)C)C2=CN=CC3=C2C=NN3C4=CC=C(F)C=C4
Molecular Formula
C20H16FN5O3S
Molecular Weight
425.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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