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CCR1 antagonist 9

Product Specifications

CAS Number

1220026-26-5

Target

CCR

Related Pathways

Microbiology/Virology, GPCR/G Protein, Immunology/Inflammation

Purity

0.9913

Bioactivity

CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. It exhibits an IC50 of 6.8 nM for CCR1 inhibition in calcium flux assays and an IC50 of 30 μM for hERG.

Smiles

O=C(NCC=1C=CN=C(C1)S(=O)(=O)C)C2=CN=CC3=C2C=NN3C4=CC=C(F)C=C4

Molecular Formula

C20H16FN5O3S

Molecular Weight

425.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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